Peptides suppressing the function of the immune system,...

Details Peptides suppressing the function of the immune system,... Peptides suppressing the function of the immune system,...

C - Chemistry, Metallurgy

07

K

530/5, 530/5.08,

C07K 5/10 (2006.01) C07K 5/068 (2006.01) C07K 5/08 (2006.01) C07K 5/09 (2006.01) C07K 5/11 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1327867

NOVEL PEPTIDES SUPPRESSING THE FUNCTION OF THE IMMUNE SYSTEM, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME Abstract The invention relates to novel peptides and their acid addition salts, suppressing the function of the immune system, pharmaceutical compositions containing these peptides as well as to a process for preparing these peptides and compositions. The peptides are represented by formulae (1) to (16): D-Arg-Lys-D-Asp, (1) Arg-D-Lys-Asp, (2) D-Arg-D-Lys-D-Asp, (3) Arg-D-Lys-D-Asp, (4) D-Arg-Lys-Asp, (5) D-Arg-D-Lys-Asp, (6) Arg-Lys-D-Asp, (7) Arg-Lys-D-Asp-Val, (8) Arg-Lys-Asp-D-Val, (9) D-Arg-Lys-Asp-Val, (10) Arg-D-Lys-Asp-Val, (11) Lys(Arg)-Asp, (12) Lys(Arg)-D-Asp, (13) Arp-Lys(Arg)-Asp, (14) Arg-Lys-Asp(Val), (15) and Arg-Lys-D-Asp(Val) (16) The novel peptides are useful for the therapy of diseases where the decrease in the activity of the immune system is desirable.

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