C - Chemistry – Metallurgy – 12 – P
Patent
C - Chemistry, Metallurgy
12
P
195/86
C12P 7/42 (2006.01) C12P 7/62 (2006.01) C12P 17/06 (2006.01)
Patent
CA 1186647
ABSTRACT OF THE DISCLOSURE Compounds of formula (I): Image (I) Image , that is to say M-4 carboxylic acid and M-4' carboxylic acid, as well as pharmaceutically acceptable salts and esters thereof and the corresponding ring closed lactones may be prepared by contacting an ML-236B compound with a microorganism of the genus Nocardia or a cell-free, enzyme-containing extract thereof and then, if necessary, subjecting the resulting product to one or more of the following reactions: hydrolysis, salification, esterification and lactonisation.
415650
Tanaka Minoru
Terahara Akira
Marks & Clerk
Sankyo Company Limited
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