Substituted 4-benzylpiperazinyl compounds

Details Substituted 4-benzylpiperazinyl compounds Substituted 4-benzylpiperazinyl compounds

C - Chemistry, Metallurgy

07

D

167/180, 260/235

C07D 498/08 (2006.01) A61K 31/395 (2006.01)

Patent

CA 1254198

Substituted 4-benzylpiperazinyl compounds Abstract of the Disclosure 3-W-Rifamycin SV and S compounds, wherein W is a piperazin-l-yl radical of the formula Image (II) wherein R1 and R2 are C1-C4alkyl and R3, R4 and R5 are hydrogen or C1-C4alkyl, or R2 together with R3 or R3 together with R4 are buta-1,3-dien-1,4-ylene, trimethylene or tetramethylene, each of which is unsubstituted or substituted by C1-C4alkyl, and R1, R4 and R5 or R1, R2 and R5 are hydrogen or C1-C4alkyl, and salts thereof, have long-term antituberculotic and antimicrobial activity.

493677

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