Expression vectors and their use for the preparation of a...

Details Expression vectors and their use for the preparation of a... Expression vectors and their use for the preparation of a...

C - Chemistry, Metallurgy

12

N

195/1.33, 195/1.

C12N 1/21 (2006.01) C07K 14/81 (2006.01) C12N 15/11 (2006.01) C12N 15/70 (2006.01) C12N 15/73 (2006.01) C12P 21/02 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1303530

ABSTRACT OF THE DISCLOSURE A transformed bacterium expressing human .alpha.1- antitrypsin is disclosed, which bacterium is transformed by a vector capable of expressing human .alpha.1-antitrypsin. The vector comprises a sequence coding for human .alpha.1- antitrypsine under the control of a promoter and a translation initiation region with the following sequence: Translation TCGATAACACAGGAACA5ATCTATG sequence Shine/Dalgano and also an origin of efficient replication effective in said bacterium.

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