Monoclonal antibody to peroxidase and hybridoma producing it

Details Monoclonal antibody to peroxidase and hybridoma producing it Monoclonal antibody to peroxidase and hybridoma producing it

A - Human Necessities

61

K

195/1.111

A61K 39/395 (2006.01) C07K 16/40 (2006.01) C12N 5/02 (2006.01)

Patent

CA 1231067

A B S T R A C T A mouse monoclonal anti-peroxidase antibody having the following characteristics: (a) of the sub-class IgG1; (b) capable of reacting with horse radish peroxidase to form a peroxidase anti-peroxidase complex without significantly interfering with the catalytic activity of the enzyme in the complex, the complex containing a molar ratio of peroxidase to antibody to at least 1,78:1, preferably at least 1,96:1, with an RZ value of at least 0,55, preferably at least 0,59; and optionally (c) produced by a hybridoma formed by fusion of spleen cells from a Balb/c mouse previously immunised with horse radish peroxidase and cells from the mouse myeloma cell line Sp2/0-Ag14. The invention also relates to a hybridoma for producing the antibody, to a method of producing the hybridoma and to a monoclonal peroxidase anti-peroxidase complex of the antibody and horse radish peroxidase.

460834

Affiliated with

Also associated with

Rating

Monoclonal antibody to peroxidase and hybridoma producing it does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Monoclonal antibody to peroxidase and hybridoma producing it, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Monoclonal antibody to peroxidase and hybridoma producing it will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1192287