Process for the in vitro reconstitution of tissues

Details Process for the in vitro reconstitution of tissues Process for the in vitro reconstitution of tissues

C - Chemistry, Metallurgy

12

N

195/46

C12N 5/00 (2006.01) C12N 5/06 (2006.01)

Patent

CA 1291433

IN THE CANADIAN PATENT & TRADEMARK OFFICE PATENT APPLICATION Entitled : Process for the in vitro reconstitution of tissues In the names of : Claire LUGASSY Jean-Paul ESCANDE Assignee : SANOFI ABSTRACT OF THE DISCLOSURE The present invention relates to a process for the in vitro reconstitution of tissues. In this process, a cell suspension prepared from the heterogeneous cell population migrating out of the system formed by a lattice and an explant of a pathological tissue, cultivated by the compact covering lattice method of culture, is incubated in the presence of collagen, said population consisting on the one hand of differentiated pathological cells and on the other hand of the two type-fibroblasts, one of them originating from the tissue stroma and the other from the lattice.

557175

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