Continuous delivery of luteinizing hormone releasing hormone...

Details Continuous delivery of luteinizing hormone releasing hormone... Continuous delivery of luteinizing hormone releasing hormone...

A - Human Necessities

61

K

167/160, 167/192

A61K 38/09 (2006.01)

Patent

CA 1339345

This invention is directed to a delivery system and a method useful for preventing pregnancy in female mammals by administering an LHRH composition. The method comprises administering during the entire follicular phase of the menstrual cycle, beginning at the time of menses, an LHRH composition and sufficient levels of an estrogenic steroid to counteract the possibility of side effects which may develop during prolonged therapy with LHRH. Following the follicular phase, at the beginning of the luteal phase, and for the entire course of the luteal phase, the LHRH/ estrogenic steroid combination administered during the follicular phase, in combination with a physiological amount of progestational steroid, is administered. The delivery system comprises means for administering the LHRH composition, estrogenic steroid and progestational steroid.

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