Penetrating topical pharmaceutical compositions containing...

Details Penetrating topical pharmaceutical compositions containing... Penetrating topical pharmaceutical compositions containing...

A - Human Necessities

61

K

167/159, 167/196

A61K 31/57 (2006.01) A61K 47/00 (2006.01) A61K 47/10 (2006.01) A61K 47/12 (2006.01) A61K 47/14 (2006.01)

Patent

CA 1216522

IMPROVED PENETRATING TOPICAL PHARMACEUTICAL COMPOSITIONS CONTAINING CORTICOSTEROIDS ABSTRACT Topical pharmaceutical compositions containing a cortico- steroid component and a penetration-enhancing vehicle are dis- closed. The vehicle comprises a binary combination of a C3-C4 diol and a "cell-envelope disordering compound". The vehicle provides marked transepidermal and percutaneous delivery of corticosteroids. A method of treating certain rheumatic and inflammatory conditions, systemically or locally, is also disclosed.

456894

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