Dna sequence participating in the regulation of the...

C - Chemistry – Metallurgy – 12 – N

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195/1.19, 195/1.

C12N 15/11 (2006.01) C07K 14/61 (2006.01) C12N 15/67 (2006.01) C12N 15/70 (2006.01)

Patent

CA 1337180

A DNA sequence of the formula 5' TTXTTCGCG 3', in which X = A, C, G or T, participates in the regulation of the expression of a DNA sequence coding for a precursor of a polypeptide. Expression vectors contain such a sequence. The periplasmic production of a polypeptide is effected in a strain of Gram-negative bacteria transformed by one of these vectors, particularly the periplasmic production of human growth hormone.

609136

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