Substituted carboxy-thiazolo¬3,2-a|pyrimidine derivatives...

Details Substituted carboxy-thiazolo¬3,2-a|pyrimidine derivatives... Substituted carboxy-thiazolo¬3,2-a|pyrimidine derivatives...

C - Chemistry, Metallurgy

07

D

260/242.01

C07D 513/04 (2006.01)

Patent

CA 1232604

Abstract of the Disclosure The present invention relates to new carboxy-thiazolo[3,2-a] pyrimidine compounds of formula I Image and their pharmaceutically acceptable salts. Typically, R is OH or lower alkoxy, R1 is hydrogen, methyl or phenyl, R2 is chlorine, bromine or methyl and R3 is phenyl which is unsubstituted or substituted by one or more methyl, ethyl, methoxy, ethoxy, fluoro or chloro substituents, or is pyridyl. The compounds have antiallergic activity and are useful in the prevention and treatment of, for example, bronchial asthma, allergic rhinitis, hay fever, urticaria and dermatosis.

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