Treatment of androgenic alopecia with 17beta-n-...

Details Treatment of androgenic alopecia with 17beta-n-... Treatment of androgenic alopecia with 17beta-n-...

A - Human Necessities

61

K

167/227

A61K 31/56 (2006.01) A61K 31/58 (2006.01)

Patent

CA 1302277

ABSTRACT OF THE INVENTION 17.beta.-N-monosubstituted-carbamoyl-4-5.alpha.- androst-1-en-3-ones of the formula Image I wherein R1 is selected from hydrogen, methyl and ethyl and R2 is a branched chain alkyl of from 3-12 carbons, and R', R", R''' are hydrogen or methyl are active as testosterone 5.alpha.-reductase inhibitors and are useful topically for treatment of androgenic alopecia.

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