Process for preparing hybridoma cells which produce...

Details Process for preparing hybridoma cells which produce... Process for preparing hybridoma cells which produce...

C - Chemistry, Metallurgy

12

N

195/1.109

C12N 5/18 (2006.01) C07K 16/30 (2006.01)

Patent

CA 1312024

- 25 - Abstract "A process for preparing hybridoma cells which produce tumour-specific monoclonal antibodies" High-yielding hybridoma cell lines which secrete monoclonal antibodies capable of binding to tumour cells of one or more types, but not normal cells can be obtained more readily by fusing myeloma cells with antibody-forming cells isolated from an animal immunized with tumour antigens, which has previously been made immunological tolerant to normal cell antigens, comprising the total antigens, or at least a proportion of the total antigens, of the normal cells corresponding to the tumour cells chosen as the source of immunizing antigens.

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