Method for increased production of penicillin acylase and...

Details Method for increased production of penicillin acylase and... Method for increased production of penicillin acylase and...

C - Chemistry, Metallurgy

12

N

195/1.14, 195/1.

C12N 15/00 (2006.01) C12N 1/20 (2006.01) C12N 9/84 (2006.01) C12N 9/86 (2006.01)

Patent

CA 1222708

GH16 Abstract METHOD FOR INCREASED PRODUCTION OF PENICILLIN ACYLASE AND PLASMID EMPLOYED THEREIN A method is provided for enhancing penicillin acylase production wherein a Bacillus subtilis plasmid containing an insert of a chromosomal DNA fragment of Bacillus megaterium which includes the appropriate gene foe enhancing penicillin acylase production is cloned into Bacillus megaterium and the Bacillus megaterium containing the above plasmid is employed in the production of penicillin acylase. A plasmid, method for forming same and host plasmid combination which are useful in the above method are also provided.

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