Reflective particle-containing solvent extraction reagent...

Details Reflective particle-containing solvent extraction reagent... Reflective particle-containing solvent extraction reagent...

G - Physics

01

N

150/14, 150/3

G01N 33/52 (2006.01) G01N 31/22 (2006.01) G01N 33/84 (2006.01)

Patent

CA 1225574

ABSTRACT A solvent extraction composition for determining an analyte in a liquid sample is disclosed. The composition com- prises (a) a plurality of solid, reflective particles, (b) at least one substance which comprises an extraction solvent for and a. least one substance which effects a detectable response to the analyte, and (c) a binder which is permeable to the analyte or a reaction product thereof in which the particles, extraction solvent and analyte-responsive substance are dis- persed. Preferably, the composition is used to determine an ionic analyte by incorporating an analyte-responsive substance such as a crown ether. The invention further provides a test device or analytical element which includes a single, integral matrix comprising the composition of the invention. This device can include other layers, if desired, but is completely effective in the absence of other layers to provide a quantita- tive detectable response to the presence of the analyte under assay. Doc. 2449-A

461952

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