Transdermal multipolymer drug delivery system

Details Transdermal multipolymer drug delivery system Transdermal multipolymer drug delivery system

A - Human Necessities

61

L

128/104, 167/159

A61L 15/44 (2006.01) A61F 13/02 (2006.01) A61K 9/70 (2006.01) A61L 15/18 (2006.01) A61L 15/58 (2006.01)

Patent

CA 1338660

A dermal composition comprising a drug, a multi-polymer of vinyl acetate, polyethylene and optionally one or more monomers, a natural or synthetic rubber and a tackifying agent. The ratio of the multipolymer to the rubber is, respectively, about 1:1 to about 10:1 and more preferably, 1:1 to 5:1 and more preferably 3:1. The dermal composition can optionally contain a crosslinking agent, tackifiers, penetration enhancers and other ingredients known for use in adhesives for the transdermal delivery of drugs. The dermal compositions can be produced by a variety of methods known in the preparation of drug containing adhesive preparations including the homogenous mixing of the multi-polymer, drug and optional crosslinking agent and additional ingredients in aqueous solution followed by removal of excess water.

586690

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