Nitrofurantoin dosage form

A - Human Necessities – 61 – K

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167/154, 167/237

A61K 31/415 (2006.01) A61K 9/50 (2006.01)

Patent

CA 1288050

NITROFURANTOIN DOSAGE FORM Vikram S. Patel Harry L. Weiles ABSTRACT The invention involves a combination sustained release/rapid release pharmaceutical capsule for oral administration of nitrofurantoin comprising, in a capsule shell, a first layer of a first particulate mixture comprising nitrofurantoin, polyvinylpyrrolidone and carboxy- vinylpolymer; and a second layer of a second particulate mixture comprising macrocrystalline nitrofurantoin.

539706

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