Process for preparing rimantadine

Details Process for preparing rimantadine Process for preparing rimantadine

C - Chemistry, Metallurgy

07

C

260/235.95

C07C 209/40 (2006.01) A01N 33/04 (2006.01) A61K 31/13 (2006.01) B01J 23/42 (2006.01) C07C 211/00 (2006.01) C07C 211/19 (2006.01) C07B 61/00 (2006.01)

Patent

CA 1220198

Title PROCESS FOR PREPARING RIMANTADINE Abstract of the Disclosure A low temperature and pressure process for preparing rimantadine in high yields from 1-adamantyl methyl ketoxime is provided. The process comprises contacting a solution of the ketoxime with hydrogen in the presence of a platinum on carbon catalyst at a low temperature and pressure, e.g., room temperature and a pressure of about 25-115 psia (170-790 KPa) are pre- ferred.

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