Bioassay for toxic substances

Details Bioassay for toxic substances Bioassay for toxic substances

C - Chemistry, Metallurgy

12

Q

150/15, 73/55

C12Q 1/32 (2006.01) G01N 33/50 (2006.01)

Patent

CA 1268407

BIOASSAY FOR TOXIC SUBSTANCES ABSTRACT OF THE DISCLOSURE An assay method is disclosed to test for the presence of toxic substances in environmental samples. The assay uses a suspension of mitochondrial membranes carrying enzymes which can be driven by reverse electron transfer to reduce NAD+ to NADH. The competency of the mitochondrial membrane to accomplish this reduction in the presence of the environmental sample is measured spectrophotometrically to test for toxicants.

526084

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