Hexa- and octahydro-4,7-epoxyisobenzofuran-1-01 and hexa-...

Details Hexa- and octahydro-4,7-epoxyisobenzofuran-1-01 and hexa-... Hexa- and octahydro-4,7-epoxyisobenzofuran-1-01 and hexa-...

C - Chemistry, Metallurgy

07

D

260/367.2, 260/3

C07D 491/18 (2006.01)

Patent

CA 1167462

ABSTRACT New compounds having the formula Image wherein R3 is -?- or Image ; x is 0 or 1; and the dotted line is an optional double bond. These compounds are useful as cardio- vascular agents. They are also useful as intermediates in the preparation of compounds of the formula Image wherein R1 is hydrogen or lower alkyl; R2 is -CHO, -CH2OH or -CH=CH-R3-lower alkylene-CH3; R3 is keto or hydroxymethyl; and the dotted line is an optional double bond, which are themselves useful as cardiovascular agents.

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