Triazine compounds having cardiovascular activity

Details Triazine compounds having cardiovascular activity Triazine compounds having cardiovascular activity

C - Chemistry, Metallurgy

07

D

167/216, 260/248

C07D 253/06 (2006.01) A61K 31/53 (2006.01) C07C 51/15 (2006.01) C07C 63/70 (2006.01) C07D 253/075 (2006.01)

Patent

CA 1261328

ABSTRACT Compounds of Formula I are novel and useful as cardiovascular agents, particularly anti-arrhythmic agents: Image (I) or the 5-amino tautomer thereof or a salt of either, wherein R1 is C1-10 alkyl, C2-10 alkenyl, C2-10alkynyl or C3-10cycloalkyl, any of which is optionally substituted, and R2 to R6 are independently selected from hydrogen, halogen atom, C1-6 alkyl, alkenyl or alkynyl (all optionally substituted by one or more of halogen, hydroxy and aryl, amino, mono- or di-substituted amino, alkoxy (optionally substituted by one or more of halogen, hydroxy and aryl), alkenyloxy, acyl, acyloxy, cyano, nitro, aryl and alkylthio groups or any adjacent two of R2to R6 are linked to form a (-CH=CH-CH=CH-) group.

466473

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