Heterodimeric transforming growth factor-beta

Details Heterodimeric transforming growth factor-beta Heterodimeric transforming growth factor-beta

C - Chemistry, Metallurgy

07

K

530/7.1

C07K 14/495 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1338077

A polypeptide transforming growth factor found in porcine platelets, having activity in the TGF-.beta. assay and a molecular weight of about 25 kDa. The factor is a heterodimer, one chain of which has an N-terminal sequence very different from human platelet TGF-.beta., and the other chain of which has an N-terminal sequence identical to that of human platelet TGF-.beta.. The factor is purified using gel filtration and reverse phase HPLC.

557717

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