C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/200, 167/227
C07D 471/08 (2006.01) A61K 31/44 (2006.01) C07C 239/00 (2006.01) C07D 451/00 (2006.01)
Patent
CA 1336428
The present invention provides a compound of formula (I): Image (I) or a pharmaceutically acceptable salt thereof, wherein one of R1, R2, R3 and R4 represents a hydrocarbon or hydrocarbyloxycarbonyl group and the remaining groups R1, R2, R3 and R4 independently represent hydrogen, hydrocarbon, hydrocarbyloxycarbonyl, halogen, hydroxy or C1-6 alkoxy, or R1 and R2 or R3 and R4 may together represent the residue of a carbocyclic ring; R5 and R6 independently represent hydrogen, hydrocarbon, hydroxy or fluoro; R7 represents hydrogen or C1-3 alkyl; and R8 represents methyl or ethyl; which compounds are useful as anticonvulsant agents and in the treatment of neurodegenerative diseases.
574661
Baker Raymond
Britcher Susan F.
Leeson Paul D.
Merck Sharp & Dohme Limited
Swabey Ogilvy Renault
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