Paralog affinity chromatography

Details Paralog affinity chromatography Paralog affinity chromatography

G - Physics

01

N

150/8, 530/1.14,

G01N 33/68 (2006.01) B01D 15/08 (2006.01) B01J 20/32 (2006.01) C07K 1/22 (2006.01) G01N 30/00 (2006.01) G01N 30/02 (2006.01)

Patent

CA 1339768

-23- A method for affinity chromatography or adsorption of a designated analyte utilizes a paralog as the affinity partner. The immobilized paralog can be used in purification or analysis of the analyte; the paralog can also be used as a substitute for antibody in an immunoassay. The paralog is identified by screening candidate peptide sequences of 4-20 amino acids for specific affinity to the analyte.

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