Method for obtaining protective antigens against bordetella...

Details Method for obtaining protective antigens against bordetella... Method for obtaining protective antigens against bordetella...

C - Chemistry, Metallurgy

12

N

167/137, 195/1.3

C12N 9/88 (2006.01) A61K 38/57 (2006.01) A61K 39/10 (2006.01) C07K 14/235 (2006.01) C12N 5/00 (2006.01) A61K 39/00 (2006.01)

Patent

CA 1341332

The invention relates to adenylate cyclase preparations comprising at least one adenylate cyclase selected from the group consisting of an active adenylate cyclase having a molecular weight (Mr) of about 43 ~ 4.3 - 45 ~ 4.5 kDa or an inactive adenylate cyclase having a molecular weight (Mr) of about 43 ~ 4.3 kDa Preferably, the active and inactive adenylate cyclase are obtained from B.parapertussis. The invention also relates to vaccine compositions for preventing infections caused by Bordetella which comprise the adenylate cyclase preparations referred to previously.

597153

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