Pyrazolo¬4,3-d|pyrimidine derivative, process for its...

Details Pyrazolo¬4,3-d|pyrimidine derivative, process for its... Pyrazolo¬4,3-d|pyrimidine derivative, process for its...

C - Chemistry, Metallurgy

07

D

167/220, 260/242

C07D 487/04 (2006.01) A61K 31/505 (2006.01)

Patent

CA 1254558

ABSTRACT OF THE DISCLOSURE A pyrazolo[4,3-d]pyrimidine derivative having the formula: Image (I) wherein R1 is lower alkyl or phenyl, R2 is -A-CO2R21 (wherein A is alkylene having from 1 to 3 carbon atoms which is unsubstituted or substituted by methyl, and R21 is lower alkyl having from 1 to 4 carbon atoms), -CH2CO-phenyl, a saturated or unsaturated, straight-chain or branched aliphatic group having from 3 to 16 carbon atoms, phenyl-lower alkyl, -CH2CN, chloro substituted phenyl-lower alkyl, or Image (wherein R22 is hydrogen or lower alkyl), and R3 is a saturated or unsaturated, straight chain or branched aliphatic group having from 2 to 22 carbon atoms, phenyl-lower alkyl, benzyloxy substituted phenyl-lower alkyl, unsubstituted or lower alkyl substituted phenyl-methyloxyethyl, cyclohexyl-cyclohexyl, methylcyclohexyl, 3-thia-n-heptyl (or 2-n-butylthioethyl) 3,6- dioxadecyl, 4-oxo-n-pentyl, or 2-hydroxethyl.

477931

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