Diverting flow chamber

B - Operations – Transporting – 01 – D

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B01D 35/06 (2006.01) B03C 1/02 (2006.01)

Patent

CA 1285246

ABSTRACT OF THE DISCLOSURE A system for the magnetic separation of fragile particles, such as intact biological cells, from a fluid medium. The system includes at least one high-gradient magnetic separator having a flow chamber housing an interstitial separation matrix and associated magnetizing apparatus for coupling magnetic flux to the matrix. The magnetizing apparatus includes opposing North and South poles and field-guiding pole pieces, external to the flow chamber. The flow chamber comprises a dual-position flux- coupler operative in a first position in the capture phase and in a second position in elutriation phase. In the capture phase, the flux-coupler is positioned to permit the magnetic flux from one magnetic pole to pass through the matrix to the other magnetic pole. In the elutriation phase, the flux-coupler is positioned so that magnetic flux is diverted from the matrix.

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