C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
260/557
C07C 231/02 (2006.01) C07C 233/25 (2006.01)
Patent
CA 1297129
IMPROVED PROCESS FOR THE PREPARATION OF N-ACETYL-P-AMINOPHENOL Abstract of the Disclosure An improved process for the preparation of N-acetylp-aminophenol. p-Aminophenol is acetylated in an aqueous medium to produce a crude aqueous reaction mixture and N-acetyl-p-aminophenol product is recovered by crystal- lization from an aqueous system comprising the reaction mixture. Crystals are separated from the crude mother liquor which contains residual N-acetyl-p-aminophenol and unreacted acetic acid. According to the improvement, residual N-acetyl-paminophenol and acetic acid are recovered from the crude mother liquor by liquid-liquid extraction with a water-immiscible organic solvent to produce an extract containing N-acetyl-p-aminophenol and acetic acid. The extract is distilled to strip off the solvent and acetic acid.
494817
Mallinckrodt Inc.
Osler Hoskin & Harcourt Llp
LandOfFree
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