Heterocyclic derivatives of pyridazinone, thiadiazinone,...

Details Heterocyclic derivatives of pyridazinone, thiadiazinone,... Heterocyclic derivatives of pyridazinone, thiadiazinone,...

C - Chemistry, Metallurgy

07

D

260/244, 260/243

C07D 403/04 (2006.01) C07D 213/40 (2006.01) C07D 213/61 (2006.01) C07D 213/81 (2006.01) C07D 213/83 (2006.01) C07D 215/48 (2006.01) C07D 253/06 (2006.01) C07D 273/04 (2006.01) C07D 285/16 (2006.01) C07D 307/68 (2006.01) C07D 307/81 (2006.01) C07D 333/24 (2006.01) C07D 333/28 (2006.01) C07D 333/38 (2006.01) C07D 333/58 (2006.01) C07D 333/68 (2006.01) C07D 401/04 (2006.01) C07D 405/04 (2006.01) C07D 409/04 (2006.01) C07D 409/06 (2006.01) C07D 413/04 (2006.01) C07D 413/06 (2006.01) C07D 417/04 (2006.01)

Patent

CA 1199027

ABSTRACT Heterocyclic Compounds Heterocyclic compounds of the formula:- Image wherein A is a direct link, or is alkylene of 1 to 4 carbon atoms or alkenylene of 2 to 4 carbon atoms; wherein either X is -CR1R2- and Y is -O-, -S- or -NR3-, wheren R1, R2 and R3, which may be the same or different, each is hydrogen or alkyl of up to 4 carbon atoms; or X is -O-, -S- or -NH- and Y is -CR1R2- wherein R1 and R2 have the meanings stated above; and wherein Het is a 5- or 6- membered heterocyclic ring containing 1, 2 or 3 heteroatoms selected from nitrogen, oxygen or sulphur atoms, which ring may be unsubstituted or may bear one or two substituents as set out in claim 1, provided that when X is -CR1R2- and A is a direct link, Het is not unsubstituted 2-furyl; and salts thereof where appropriate; processes for their manufacture and pharmaceutical compositions containing them. The compounds possess cardiotonic and/or antihypertensive activity.

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