Method for the extraction of silymarin from plants

Details Method for the extraction of silymarin from plants Method for the extraction of silymarin from plants

C - Chemistry, Metallurgy

07

D

260/373.1, 260/3

C07D 405/04 (2006.01)

Patent

CA 1177088

ABSTRACT OF THE DISCLOSURE Silymarin (silymarin I, II, III and IV) is produced in a purity superior to that of prior methods in a new method in which a large part of the oil is removed from the fruits of Silybum marianum by cold pressing, the compressed mass is broken up, the pressed residue is extracted with anhydrous ethyl acetate and the ethyl acetate extract is evaporated, the residue therefrom is defatted, a methanolic solution of the defatted residue is separated with a chlorine substituted lower alkane, and silymarin is recovered from the aqueous methanolic phase.

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