Nitroimidazolyl intermediates useful in the preparation of...

C - Chemistry – Metallurgy – 07 – D

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C07D 233/91 (2006.01) A61K 31/415 (2006.01) C07D 403/06 (2006.01)

Patent

CA 1260949

ABSTRACT OF THE DISCLOSURE A compound of formula (VII) Image (VII) wherein R1 represents hydrogen or alkyl; R2, R3, R4, and R5 each represent hydrogen, alkyl, aryl, alkaryl or aralkyl; Z represents halogen. These compounds are useful as intermediates in the preparation of nitro imidazolyl aziridino propanols useful in treatment of cancer patients by radiotherapy or chemotherapy.

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