Secretion of correctly processed human growth hormone in...

Details Secretion of correctly processed human growth hormone in... Secretion of correctly processed human growth hormone in...

C - Chemistry, Metallurgy

12

N

195/1.32

C12N 15/00 (2006.01) C07K 14/61 (2006.01) C12N 15/70 (2006.01) C12N 15/78 (2006.01) C12P 21/00 (2006.01)

Patent

CA 1267099

ABSTRACT The production of mature hGH In E. coli and Pseudomonas strains transformed by a plasmid which encodes pre hGH (comprising the signal polypeptide and the hormone itself) is described. These prokaryotes process the pre-hGH to cleave the signal sequence and, thereby, produce mature hGH.

452697

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