Monoclonal antibody

C - Chemistry – Metallurgy – 12 – P

Patent

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195/1.112

C12P 21/08 (2006.01) C07K 16/28 (2006.01) C12N 5/20 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1306430

ABSTRACT The present invention relates to two monoclonal antibodies which are broadly reactive with all normal human peripheral blood T and B lymphocytes and monocytes and to hybridoma cell lines which produce these monoclonal antibodies. These monoclonal antibodies are designated WM-66 and WM-63 and the respective hybridoma cell lines are designated F56-2D7 (ECAC 88101104) and F56-4D6 (ECACC 88101103). Both of these monoclonal antibodies react with a previously unrecognised human leucocyte differentiation antigen. The relative molecular mass of the antigen recognised by WM-66 is approximately 65 kilodaltons.

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