Thietanyl-substituted amides

C - Chemistry – Metallurgy – 07 – D

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260/327, 99/140.

C07D 331/04 (2006.01) A23L 1/236 (2006.01)

Patent

CA 1285282

ABSTRACT This invention is directed to food sweeteners of the formula: Image wherein A is hydrogen, alkyl containing 1-3 carbon atoms, hydroxyalkyl containing 1-3 carbon atoms, alkoxymethyl wherein the alkoxy contains 1-3 carbon atoms or carbalkoxy wherein the alkoxy group contains 1-3 carbon atoms; A' is hydrogen or alkyl containing 1-3 carbon atoms; A and A' taken together with the carbon atom to which they are attached form cycloalkyl containing 3-4 carbon atoms; 2 is -CH2CH2-; -CH=CH; Image -CH(OH)-CH2; -CH2O or Image ; and Y is thietanyl or alkyl-substituted thietanyl containing up to a total of 8 carbon atoms; B' is H or an amino protecting group with the proviso that when Z is Image , B.' is not H. and food acceptable salts thereof.

542196

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