Antitumour compounds from marine sponge of the genus dercitus

Details Antitumour compounds from marine sponge of the genus dercitus Antitumour compounds from marine sponge of the genus dercitus

C - Chemistry, Metallurgy

07

D

167/227, 260/273

C07D 471/04 (2006.01) A61K 31/47 (2006.01) C07D 471/06 (2006.01) C07D 513/16 (2006.01)

Patent

CA 1337424

The invention relates to novel alkaloid compounds of the formulae (I), (II) and (III): Image (I) Image Image (II) (III) wherein R1 is a group selected from -CH2CH2N(CH3)2, -CH2CH2N+(CH3)3X-, -CH2CH2N+(O-)(CH3)2, -CH=CH2, -CHO, and -COOR; X is halogen; R is hydrogen or lower alkyl; R2 is hydrogen or together with R3 is -N=CZ-S-; R3 together with R2 is -N=CZ-S- or is a group selected from -NH2, -NHCOR, and hydrogen; Z is NO2, NH2 or hydrogen; R4 is hydrogen or lower alkyl, and R5 is a group selected from hydrogen, lower alkyl and lower alkanoyl. These compounds and pharmaceutical compositions containing therapeutic effective amounts thereof are useful as antitumor and immunomodulatory medications.

592400

Affiliated with

Also associated with

Rating

Antitumour compounds from marine sponge of the genus dercitus does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Antitumour compounds from marine sponge of the genus dercitus, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Antitumour compounds from marine sponge of the genus dercitus will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1217206