Process for solubilization, purification and...

Details Process for solubilization, purification and... Process for solubilization, purification and...

C - Chemistry, Metallurgy

07

K

167/129, 530/15.

C07K 1/113 (2006.01) C07K 14/035 (2006.01)

Patent

CA 1285699

29,918 TITLE: PROCESS FOR SOLUBILIZATION, PURIFICATION AND CHARACTERIZATION OF PROTEIN FROM INSOLUBLE PROTEIN AGGRE- GATES OR COMPLEXES AND COMPOSITIONS OF MATTER THEREFROM ABSTRACT OF THE DISCLOSURE This invention discloses a novel process for the solubilization, purification and characterization of a pro- tein or proteins from insoluble protein aggregates or com- plexes. The novel process comprises the use of a dissociating step gradient which can be followed by further purification and concentration. Also disclosed are compositions of matter and vaccines comprising one or more proteins purified ac- cording to the novel process of this invention.

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