Substituted 3,4-diamino-1,2,5-thiadiazoles having histamine...

C - Chemistry – Metallurgy – 07 – D

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260/277, 260/301

C07D 285/10 (2006.01) C07D 417/00 (2006.01) C07D 417/12 (2006.01)

Patent

CA 1228067

Abstract of the Disclosure Histamine H2-receptor antagonists of the formula Image I wherein A, m, Z, n and R1 are as defined herein, and their nontoxic pharmaceutically acceptable salts, hydrates and solvates are novel anti-ulcer agents which are prepared by ring closure o' a substituted ethanediimidamide of the formula Image II

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