A - Human Necessities – 61 – F
Patent
A - Human Necessities
61
F
167/156, 167/251
A61F 13/00 (2006.01) A61K 9/70 (2006.01) A61K 31/21 (2006.01)
Patent
CA 1166960
Abstract The present invention provides a trans-dermal delivery pad for nitroglycerin administration, specifically a microsealed, trans-dermal nitroglycerin pad having a backing which is impervious to nitroglycerin absorption and transport and a silicon matrix affixed thereto, said silicone polymer matrix being of cross-linked silicone rubber having from about 10 to 200 micron microsealed compartments being formed by in situ cross-linking of the silicone rubber after it is mixed with a hydrophilic solvent system containing the nitroglycerin and a hydrophilic solvent which enhances nitroglycerin dispersion and transport.
383561
Cooney James G.
Sanvordeker Dilip R.
Wester Ronald C.
Osler Hoskin & Harcourt Llp
Searle (g. D.) & Co.
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