Peptides aiding nerve regeneration

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

530/7.06, 530/7.

C07K 7/06 (2006.01) C07K 14/685 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1265900

Abstract of the Disclosure A heptapeptide of the formula: A1-A2-A3- A4-Phe-Arg-Trp-A5, wherein A1 is H or acetyl; A2 is Ala, D-Ala, Nle, or Met; A3 is Glu or Gln; and A4 is His or Tyr, and A5 is NH2, Gly-NH2, or D-Ala-NH2, provided that when A3 is Glu and A4 is His, A2 cannot be Met or Nle; or a pharmaceutically acceptable salt thereof. These compounds find use in compositions for regenerating nerves.

507826

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