Thienyloxyalkylamine derivatives, process for their...

Details Thienyloxyalkylamine derivatives, process for their... Thienyloxyalkylamine derivatives, process for their...

C - Chemistry, Metallurgy

07

D

167/208, 167/242

C07D 409/06 (2006.01) A61K 31/38 (2006.01) C07D 409/14 (2006.01)

Patent

CA 1338716

Thienyloxyalkylamine derivatives of the general formula: Image I wherein -O-CH2-CH2-NR2R3 is in position 4 or 5 of the thiophene ring; R1 is hydrogen, halogen, CF3, alkyl or alkoxy; R2 and R3 are the same or different and are each alkyl, cycloalkyl, alkenyl or alkynyl each having up to 8 C atoms, or NR2R3 is a 5 to 7-membered saturated heterocyclic ring optionally containing a further hetero atom which is oxygen or nitrogen optionally substituted by an alkyl group having 1 to 3 C atoms; and n is an integer of 1 to 5; as well as their acid addition salts, are suitable for treatment of heart rhythm disturbances.

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