Substituted vinyl cephalosporins

Details Substituted vinyl cephalosporins Substituted vinyl cephalosporins

C - Chemistry, Metallurgy

07

D

260/104.1

C07D 501/24 (2006.01) C07D 501/00 (2006.01) C07D 513/04 (2006.01) C07F 9/6561 (2006.01)

Patent

CA 1340697

3-[(Z)-1-Propen-1-yl]-7-acylamido cephalosporins in which the 7-acyl group is phenylglycyl or substituted phenylglycyl are orally active antibiotics against Gram+ and Gram- bacteria. Specifically, the 3-[(Z)]-1-Propen-1-yl]-7-acylamido cephalosporins are 3-halomethyl-7-acetamido cephalosporins.

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