Dihydropyridine-5-phosphonic acid cyclic ester

C - Chemistry – Metallurgy – 07 – F

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C07F 9/547 (2006.01) A61K 31/675 (2006.01) C07D 211/90 (2006.01) C07F 9/59 (2006.01) C07F 9/6571 (2006.01) C07F 9/6574 (2006.01)

Patent

CA 1339372

A compound represented by the general formula: Image where X is a hydrogen atom, a nitro group, a trifluoromethyl group, a fluorine atom, a chlorine atom, a bromine atom or an iodine atom, A is a 1,3-propylene or 1,4-butylene group which is unsubstituted or substituted by at least one alkyl group having 1 to 3 carbon atoms, R is Image where R3 is a mono- or diphenyl lower alkyl group, and Y is an alkylene group having 2 to 6 carbon atoms, and Me is a methyl group, or its pharmaceutically acceptable salt.

463611

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