Synthetic copolymer surgical articles and method of...

A - Human Necessities – 61 – L

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400/2013, 167/32

A61L 17/00 (2006.01) A61K 9/20 (2006.01) A61L 17/12 (2006.01) A61L 27/00 (2006.01) A61L 31/00 (2006.01) C08G 63/08 (2006.01) C08G 63/64 (2006.01)

Patent

CA 1204894

SYNTHETIC COPOLYMER SURGICAL ARTICLES AND METHOD OF MANUFACTURING THE SAME ABSTRACT OF THE DISCLOSURE A triblock copolymer having a proportion of units having the formula: Image (I) as the end blocks, said formula I as an end block having a hydro- gen atom attached to the terminal oxygen atom, and the formula (I) randomly combined with a proportion of units having the formula: Image (II) as the middle block finds particular advantageous use in manufac- turing absorbable monofilament sutures and other surgical arti- cles. A surgical article is manufactured from a synthetic absorb- able copolymer formed by copolymerizing glycolide with 1,3- diox- an-2-one (trimethylene carbonate) wherein a combination of the monomers is substantially completely polymerized before the addi- tion of the other monomer in the presence of a difunctional initi- ator at or below about 180°C; glycolide is added and the tempera- ture increased up to about the melting point of poly glycolide to form a triblock copolymer with a proportion of units having the formula: Image as the end blocks, and the formula (I) randomly combined with a proportion of units having the formula: Image (II) as the middle block.

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