Pharmaceutical compositions having good stability

A - Human Necessities – 61 – K

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167/168, 167/255

A61K 31/22 (2006.01) A61K 9/20 (2006.01) A61K 31/19 (2006.01) A61K 47/02 (2006.01)

Patent

CA 1323836

Abstract PHARMACEUTICAL COMPOSITIONS HAVING GOOD STABILITY A pharmaceutical composition is provided which has excellent stability, when dispersed in water has a pH of at least about 9, and includes a medicament which is sensitive to a low pH environment such as pravastatin, one or more fillers such as lactose and/or microcrystalline cellulose, one or more binders, such as microcrystalline cellulose (dry binder) or polyvinylpyrrolidone (wet binder), one or more disintegrating agents such as croscarmellose sodium, one or more lubricants such as magnesium stearate and one or more basifying agents such as magnesium oxide.

591236

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