C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
260/492.3, 260/4
C07C 121/75 (1980.01) C07C 149/415 (1980.01)
Patent
CA 1178606
Abstract of Disclosure .alpha.-Cyanobenzyl esters of the general formula I Image (I) wherein R1 is an optionally substituted alkyl or cycloalkyl group and R2 is phenoxy, phenylthio or benzyl, are prepared by reacting a benzaldehyde of general formula II Image (II) and an acid halide of the general formula III R?CO-Hal (III) with an excess of a water soluble cyanide in a reaction medium comprising water and a substantially water-immiscible inert organic solvent in the presence of from 100 to 1000 ppm based on the weight of acid halide of formula III , of a tertiary amine.
405455
Giddings Rodney M.
Pearse Michael T.
Tissington Peter
Fetherstonhaugh & Co.
Novartis Ag
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