Norepinephrine potentiated compositions and method of use

A - Human Necessities – 61 – K

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167/179, 167/274

A61K 45/06 (2006.01) A61K 9/06 (2006.01) A61K 31/135 (2006.01) A61K 31/41 (2006.01) A61K 31/415 (2006.01)

Patent

CA 1217141

ABSTRACT OF THE DISCLOSURE Novel pharmaceutical compositions containing norepinephrine releasers such as alpha-adrenergic agonists, para-sympathomimetic agonists and carbonic anhydrase inhibitors in combination with a potentiating amount of norepinephrine are disclosed. Use of such compositions, exemplified by the combination of norepinephrine and epinephrine, in an ophthalmic solution for the treatment of glaucoma is also disclosed, as well as the use of the combination of norepinephrine and a norepinephrine releaser in the treatment of congestion in the upper respiratory tract.

452734

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