Di-t-butylphenols substituted by an alkoxy or benzyloxy...

C - Chemistry – Metallurgy – 07 – C

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167/233, 167/246

C07C 255/37 (2006.01) A61K 31/41 (2006.01) C07C 59/68 (2006.01) C07C 65/24 (2006.01) C07D 257/04 (2006.01)

Patent

CA 1325431

-35- ABSTRACT OF THE DISCLOSURE Novel compounds which are 2,6-di-t-butylphenols substituted in the 4 position by an alkoxy or benzyloxy group or a benzylthio group, which alkoxy or benzyloxy group is directly substituted by a tetrazole ring, and which benzylthio group is directly substituted by carboxy or tetrazolyl are useful as inhibitors of leukotriene biosynthesis and as antiallergic agents. Synthetic intermediates for preparing such compounds are also described.

580766

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