4-aroylimidazolidin-2-ones

Details 4-aroylimidazolidin-2-ones 4-aroylimidazolidin-2-ones

C - Chemistry, Metallurgy

07

D

260/315, 260/305

C07D 233/32 (2006.01) C07D 233/38 (2006.01) C07D 403/02 (2006.01) C07D 403/06 (2006.01) C07D 405/06 (2006.01) C07D 409/06 (2006.01)

Patent

CA 1175829

NOVEL 4- AROYLIMIDAZOLIDIN-2-ONES ABSTRACT This invention relates to aroyl-2-imidazolidinones of the following general structure which are useful as cardiotonics and antihypertensive agents Image whereln Ar is furanyl, thlenyl, 1H pyrrolyl, or phenyl optionally substituted with one or two X groups; X is halogen, hydroxy, lower alkyl, lower alkoxy, lower alkkyl- thio, lower alkylsulfoxide, lower alkylsulphone, trifluoro- methyl, -S02N(R2) 2, NR3R5, pyrrolidino, piperidino, morpholino, piperazino or N'-alkyl-piperazino; R is hydrogen, lower alkyl, lower alkylcarbonyl or benzoyl; each of R1, R2, R5 and R4 is hydrogen or lower alkyl; T is an oxygen atom or a dlvalent sulfur atom; and the pharmaceutically acceptable salts thereof,

414709

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