Pharmaceutical article of manufacture comprising a bisulfite...

A - Human Necessities – 61 – K

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A61K 9/02 (2006.01) A61K 31/615 (1990.01)

Patent

CA 1285879

ABSTRACT OF THE DISCLOSURE An aqueous suspension of pure 5-aminosalicylic acid adapted for rectal administration is rendered storage stable against color formation by storing the suspension in a single dose polyethylene bottle adapted for rectal administration of the suspension, in a substantially oxygen-free atmosphere and in the presence dissolved therein of up to about 0.25% of bisulfite and protecting the suspension from exposure to atmospheric oxygen during storage by sealing the plastic bottle, in a substantially oxygen-free atmosphere, in a plastic pouch having a low oxygen transmission rate.

530155

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