Immunoassay for estriol-3-sulfate

G - Physics – 01 – N

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G01N 33/531 (2006.01) C07J 1/00 (2006.01) C07J 41/00 (2006.01) G01N 33/537 (2006.01) G01N 33/543 (2006.01) G01N 33/548 (2006.01) G01N 33/74 (2006.01)

Patent

CA 1285866

- 29 - ABSTRACT IMMUNOASSAY FOR ESTRIOL-3-SULFATE The invention provides a process for producing an antibody having a specificity to estriol-3-sulfate. The process comprises administering a 6-substituted-estriol-3-sulfate protein conjugate of the formula: Image (I) wherein A is =N-O- or -O-CO-, n is an integer of 1 to 4 and -NH-P is the residue of a protein excluding a hydrogen atom in the amino form therefrom, parenterally to a living body of a vertebrate animal so as to produce the antibody in the living body and collecting a body fluid comprising the antibody from the living body. The invention also relates to the conjugate itself and its use in immunoassay for estriol-3-sulfate.

493315

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