Crystallization process

Details Crystallization process Crystallization process

C - Chemistry, Metallurgy

07

D

260/104.1

C07D 501/46 (2006.01) C07D 501/00 (2006.01) C07D 501/12 (2006.01)

Patent

CA 1239389

Abstract Ceftazidime pentahydrate is obtained in purified crystalline form in a process comprising acidification of an aqueous solution of ceftazidime to about the optimum pH for nucleation of between about 4.0 and about 4.7 and maintenance at the optimum pH during crystallization. The crystalline product obtained exhibits enhanced stability toward polymer formation when stressed.

494634

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